Islets and Glucose Homeostasis

Islets and Glucose Homeostasis

Copyright © 2015 Tien-Jyun Chang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Diabetes mellitus is a chronic progressive metabolic disease, resulting from both insulin resistance and the dysfunction of beta-cells. Beta-c...

Glucose homeostasis is regulated by donor islets in xenografts.

Bisphosphonates and glucose homeostasis

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Glucose homeostasis and p75NTR

The p75 neurotrophin receptor (p75), a member of the tumor necrosis factor receptor (TNFR) superfamily, was originally identified as a receptor for neurotrophins and is expressed in the nervous system and in many non-neuronal tissues such as white adipose tissue (WAT), skeletal muscle and liver. Although the biological functions of p75 in the nervous system have been extensively studied, the mu...

MONOPHASIC STATE OF INSULIN SECRETION IN ISOLATED RAT ISLETS OF LANGERHANS BY K+, Ca2+ AND GLUCOSE

Isolation of rat islets of Langerhans was carried out by using collagenase and the destruction of exocrine tissue was performed through the injection of Hanks' solution into the common bile duct. The identification of the islets was done by techniques including the use of a stereomicroscope against a black background. Vital staining was done by an injection of neutral red solution through t...